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Warfarin's considerably less powerful R-enantiomer is metabolized partially by CYP3A4 (as well as CYP1A2 and CYP2C19). Check INR much more routinely if coadministered with inhibitors of these isoenzymes and alter warfarin dose if essential.A 2020 review reported that modafinil features a modest impact on memory updating, though the influence is lit

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